Iboga: At the Crossroads of the Jungle and the Laboratory

Ibogaine, the primary alkaloid of iboga, a psychoactive African root bark, has been administered to thousands of people in the last three decades as an experimental medication with promising efficacy[1] in the treatment of substance use disorders, depression and other medical diagnoses. Unfortunately, some recent reports have suggested that Tabernanthe iboga, the most common plant source of ibogaine, is becoming much less accessible for traditional knowledge holders, and may possibly become endangered in the Gabonese wilderness.